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关键词： 征稿函   文献索引   复合影响因子   期刊网络出版   中国知网   学术期刊   工程技术   学术影响力  

摘要： 《食品女全质量检测学报》(半月刊)创刊于2010年,是全国首本专注于食品安全与质量领域研究与开发的学术期刊,连续入选中国科技核心期刊库、中国知网学术期刊网络出版总库、万方数据库等,以及国际上英国CABI、英国FSTA、俄罗斯AJ等知名专业文献索引系统。在2020版《中国学术期刊影响因子年报(自然科学与工程技术-2020版)》中的复合影响因子为1.347,质量水平和学术影响力增幅显著,获得专家学者一致好评。目前为中国科技核心期刊。

关键词： 课程思政   生物化学   多元教学方法  

摘要： 教师需要充分意识到思政教育融入专业课程的必要性与意义。本文根据生物化学课程实施课程思政的教学实践,将爱国主义、民族自豪感、法律意识、职业道德和科学素养等五方面思政教育融入教学内容。在此基础上,通过分析课程思政提高教学方法改革的效果,从而阐明课程思政的必要性与可行性,为探索专业课课程思政提供了教学实践参考。

关键词： 高效液相色谱法   食品分析   营养成分   食品添加剂  

摘要： 高效液相色谱法属于色谱分析法的一个重要组成,以经典液相色谱为基础,在食品检测中得到了广泛运用。本文描述了高效液相色谱法在食品分析工作中的应用,主要分析食品营养成分检测、农药残留检测和食品添加剂检测等。

关键词： Methionine aminopeptidase   MetAP   Vibrio   Drug discovery   Cholera  

摘要： Methionine aminopeptidases (MetAPs) have been recognized as drug targets and have been extensively studied for discovery of selective inhibitors. MetAPs are essential enzymes in all living cells. While most prokaryotes contain a single gene, some prokaryotes and all eukaryotes including human have redundancy. Due to the similarity in the active sites of the MetAP enzyme between the pathogens and human limited the success of discovering selective inhibitors. We recently have discovered that MetAPs with small inserts within the catalytic domain to have different susceptibilities against some inhibitors compared to those that do not have. Using this clue we used bioinformatic tools to identify new variants of MetAPs with inserts in pathogenic species. Two new isoforms were identified in Vibrio species with two and three inserts in addition to an isoform without any insert. Multiple sequence alignment suggested that inserts are conserved in several of the Vibrio species. Two of the three inserts are common between two and three insert isoforms. One of the inserts is identified to have "NNKNN" motif that is similar to well-characterized quorum sensing peptide, "NNWNN". Another insert is predicted to have a posttranslational modification site. Three Vibrio proteins were cloned, expressed, purified, enzyme kinetics established and inhibitor screening has been performed. Several of the pyridinylpyrimidine derivatives selectively inhibited MetAPs with inserts compared to those that do not have, including the human enzyme. Crystal structure and molecular modeling studies provide the molecular basis for selective inhibition. (c) 2020 Elsevier Masson SAS. All rights reserved.

关键词： 食品化学   课程实验   教学改革  

摘要： 食品化学课程实验是高等学校食品类相关专业重要的专业实验课程之一。针对食品化学课程实验教学现状及存在问题,围绕课程内容调整、实验场地及设备的改进、教学模式的改革、考核方式的改进四个方面对食品化学课程实验进行了探索与研究。

关键词： ICL system   Grazing   Cover crops   Soil enzymes   Microbial community structure  

摘要： Integrated crop-livestock (ICL) system that include livestock grazing of crop residue and/or cover crops is an agricultural practice that manage crops and livestock on a single farm. Integrated crop-livestock system can provide opportunities to restore ecological services and interactions among different land-use systems to enhance agricultural ecosystems' efficiency. These systems help to enhance nutrient cycling, soil health, and protect the environment. This study was conducted at four different locations to understand the synergistic effect of the ICL systems on soil health by keeping native grasslands as a reference. Data showed that ICL system significantly increased the cold-water soluble carbon (CWC) by 44.2, 126.2, and 94.8% than the control (CNT) treatment at sites 1, 2, and 4, respectively. At site 2 and 4, the ICL system significantly increased the hot-water soluble carbon (HWC) by 265, and 104% higher compared to the CNT, respectively. The total phospholipid fatty acid (PLFA) abundance was 95.4 and 25.5% higher under ICL system compared to the CNT at site 3 and 4, respectively. ICL system significantly increased the dehydrogenase, fluorescein diacetate, urease, and beta-glucosidase activity compared to CNT at all the locations. The type of carbon (C) input (easily mineralizable organic matter), substrate availability (labile C and nitrogen), enzyme activities, and suitable soil environment or ecology of the system have been found to be the major influencing factors that determine the shifts in bacterial community structure and composition of the soil. This research finds a clear correlation between the ICL systems and the microbial communities, and soil health. It provides a viable option for restoring the natural ecosystem and achieving food security.

关键词： 色谱技术   食品分析   检测  

摘要： 随着食品行业的发展,相关的分析检测工作量逐渐增多,需要借助色谱技术对食品进行分析和检测,并将先进技术运用在工业生产过程中,从根本上提升食品检测的有效性。

关键词： 工程教育专业认证   食品生物化学   教学改革  

摘要： 在工程教育专业认证背景下,高等教育必须实施教学改革,才能满足工程人才培养的需要。《食品生物化学》是食品专业学生的必修课,本文从理论课教学和实验教学两个方面探索了课程教学改革的主要措施。为深入贯彻OBE教学理念,理论课采用混合式教学模式,充分利用网络教学资源,提高教学效率,采用学习软件与学生进行互动,检测学习效果,采用问题引导式,激发学生学习兴趣,鼓励学生运用思维导图进行知识点总结;实验课优化实验内容设置,加大综合型、设计型实验比例,提高学生理论联系实际和创新能力,优化考核体系。通过教学改革,满足新时代食品工程专业人才的需要。

关键词： 医学生物化学与分子生物学   课程思政   教学实践  

摘要： "课程思政"是新时期对高校医学生物化学和分子生物学教学提出的新要求。医学生物化学与分子生物学具有天然的"课程思政"建设优势,本文从实验教学重在实践、理论教学融入人文素养教育、联系科学前沿启发科学精神及突发公共事件的即时导入四个方面,阐述了在医学生物化学与分子生物学课程体系中融入思政教育的教学实践,以达到价值塑造、能力培养、知识传授于一体的教学目标。

关键词： Respirometer   Biochemical oxygen demand (BOD)   Oxygen uptake rate (OUR)   Real-time monitoring  

摘要： In response to the ever-increasing need for monitoring-based process control of wastewater treatment plants, an online applicable respirometer shows great promise for real-time measurement of oxygen uptake rate (OUR) and biochemical oxygen demand (BOD) measurements as a surrogate of the biodegradability of wastewater. Here, we have developed a photosensor-assisted real-time respirometric system equipped with bubble counting sensors for accurate measurement of microbial oxygen consumption in a bottle. This system can measure OUR and BOD in a bottle equipped with a tube containing NaOH solution to absorb carbon dioxide and supplied with continuous atmospheric oxygen to the bottle, which reliably supplies non-limiting dissolved oxygen (DO) for aerobic biodegradation even at high organic loads. These technical improvements allow a sensitive and rapid analytical tool offering real-time profiles of oxygen uptake rate as well as BOD measurements with an extended measurable range (0-420 mg O-2/L), enabling significant reduction or elimination of dilution steps. The respirometric system was used to elucidate the biodegradable kinetics of domestic and swine wastewaters as a function of the type and concentration of organic matters, depending on source characteristics including rapidly or slowly oxidizable organic substances by bacteria. Compared with conventional and manometric BOD methods, our method is reliable and accurate.