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关键词： Abandoned mines   Hypersaline deposits   Jarosite   Phytoremediation   Phytotoxicity   Soil quality   IBERIAN PYRITE BELT   DEHYDROGENASE-ACTIVITY   ARYLSULFATASE ACTIVITY   ENVIRONMENTAL-IMPACT   SOIL ACID   JAROSITE   PHOSPHOMONOESTERASE   ENZYME   PH   IDENTIFICATION  

摘要： Sao Domingos sulfide mine was shut down more than 50 years ago leaving behind eroded and depositional surfaces due to acid mine drainage (AMD). The aim of this study was to assess six selected sites subjected to AMD, considered phytotoxic regions characterized by vegetation scarcity. Two main criteria, nature and composition of soluble fractions and total chemistry of surficial products related to jarosites presence, enabled to set up an overall dichotomy between superficial proximal/discharge and distal/sedimentation areas. Wet and dry sieving results comparison revealed that samples have a predominant sandy texture and lithic (phyllite, quartzite and volcanic country rocks) composition. Quartz, and subordinate feldspar enrichment is also detected in the coarse silt fraction. The results also suggest that the materials under study, when subjected to the local torrential hydrologic regime, have a high mechanical vulnerability, facilitating erosion and mud transport, both critical for vegetation support, and triggering contamination transfer and dispersion. The vicinity and ground-level surfaces of discharging areas are enriched in the jarosite group minerals whereas the sedimentation ones present hypersaline aluminous tendency. The formation of jarosite is considered as an efficient positive environmental contribution to metals and metalloids sequestration/immobilization. The remediation/revegetation solutions to be adopted in each location must have into consideration these differentiating aspects. (C) 2020 The Authors. Published by Elsevier B.V.

关键词： Hepatic encephalopathy   Thymoquinone   Anxiety   Depression   Oxidative stress   OXIDATIVE STRESS   NIGELLA-SATIVA   RODENT MODEL   LIPOPOLYSACCHARIDE   INFLAMMATION   DEPRESSION   CYTOKINES   EXTRACT   ANXIETY   DAMAGE  

摘要： Hepatic encephalopathy (HE) is a cerebral function alteration in patients with liver dysfunction. The present study aimed to evaluate the therapeutic effects of thymoquinone (TQ) on behavioral deficits and its possible mechanism(s) in a thioacetamide (TAA)-induced HE model. HE was induced in male Wistar rats by intraperitoneal (i.p.) injection of TAA (200 mg/kg) for once every 48 h for 14 consecutive days. Thymoquinone (5, 10, and 20 mg/kg) was administered for seven consecutive days (i.p.) after HE induction. Anxiety and depressionlike behaviors assessed by standard paradigms respectively. Finally, their brain hippocampus sections prepared to evaluate the oxidative stress changes in rats. Data showed treatment HE rats with TQ ameliorated anxiety and depression-like behaviors. TQ administration also reduced oxidative stress due to its potential to enhance the levels of glutathione-pemxidase (GPx), catalase (CAT), and total thiol content in the hippocampus. These findings suggest that TQ has notable effects against acute hepatic failure and HE complications through modulation of oxidative stress.