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关键词： 食品生物化学   课程思政   思政元素   课程教学  

摘要： 从食品生物化学“课程思政”的必要性和实践途径进行探讨,以期在食品生物化学课程改革中提供思路与方法。

关键词： 印度籍留学生   生物化学与分子生物学   中英双语教学  

摘要： 随着我国"一带一路"战略的实施,国际留学生教育成为评价高等教育院校国际化的重要标志。生物化学与分子生物学是我校印度籍留学生临床医学专业的重要专业必修课,由于留学生存在文化差异、语言障碍,教师英文口语局限、师生沟通不畅等,在教学过程中引导学生进入教学情境、激发学习热情,对于教学环节的顺利开展至关重要。本文从印度籍留学生特点和中英双语教师教学过程中出现的问题两个角度入手,从教材选择与教学大纲的制订、教学设计与教学课件的制作、讲稿准备与试讲、教学预测与教学过程记录、学生态度与应对、考核方式六个方面提出了几点探索与体会,以供中英双语教学参考。

关键词： Organic loading   Lipids   Protein   Carbohydrates   Bioevaporation   MATTER DEGRADATION   SEWAGE-SLUDGE   PIG MANURE   STABILIZATION   AMENDMENT   COMPOST  

摘要： More food waste (FW) is desired to be treated in a certain processing period, while the degradation pattern of biochemical fractions during FW bioevaporation was significantly influenced by the organic loading (OL). Lower OL facilitated the lipids degradation, while higher OL favored the protein degradation. It was the more porous structure and abundant oxygen accelerated the lipids degradation, and the rapid proliferation of aerobic microorganisms compensated for the low protein degradation in lower OL. Detailly, 76.8% of the lipids was degraded in the trial with OL of 1.04 kg VSFW/kg TSBS (Trial A), but in the trial with OL of 3.16 kg VSFW/kg TSBS (Trial C) it was only 0.5%. For protein, the degradation was different that 17.5% of the protein was degraded in Trial A, whereas 69.1% was degraded in Trial C. Lipids degradation contributed 63.0% to the metabolic heat in Trial A, but its contribution in Trial C was only 0.5%. For protein, it contributed 4.1% to the metabolic heat in Trial A, but in Trial C it accounted for 53.6%. In addition, the degradation of carbohydrates (71.6-80.8%) and their contribution to metabolic heat (32.8-45.9%) were comparable in all trials, thus OL had little effect on carbohydrates degradation. Results from this study could provide important guideline for FW practical disposal during their biological treatment.

关键词： 网络学习空间   课程标准   混合式教学   课程资源  

摘要： “生物化学”课程是高职五年制护理专业的一门专业基础课,课程内容本身比较抽象,相对于其他课程难度较大。为满足学生学习的需要,可借助信息化、网络化的手段开发网络学习空间,通过线上、线下的混合式教学提升教学质量。

关键词： 生化工程   生物制药   生物反应器   生化分离工程   生化制剂工程  

摘要： 王义翘先生是美国麻省理工学院生物技术过程工程中心(BPEC)的创始人。在他的领导下,BPEC通过协同创新和生物化学工程(生化工程)的前沿探索,取得了显著的成就。(1)引领了生化工程进入生物制药新时代。与最初的生化工程概念相比,BPEC的重点发生了很大的转变,目标分子不再局限于抗生素、化学品和燃料等小分子,而是拓展到抗体、细胞因子、血液蛋白质和疫苗抗原等生物大分子,解决这些生物药品大规模生产所遇到的工程科学问题。(2)开启了动物细胞培养工程。当细胞生物学家忙于通过增加滚瓶的数量来扩大生产时,BPEC通过流体力学和传质分析,最大限度地减少剪切应力和扩散限制,成功地实现了动物细胞的生物反应器培养,设计出大规模培养的最佳培养基组成和添加策略,获得了蛋白质翻译后修饰随时间变化的规律,提高了动物细胞反应器的目标蛋白质产量。(3)创新了高质量生物大分子的分离纯化技术,建立了亲和膜、反胶束、电辅助分离等新方法。利用准弹性光散射技术,研究了蛋白质的再折叠和聚集机制,发明了聚乙二醇稳定再折叠中间体的新技术。(4)建立了生化工程协同创新和人才培养体系,促进了BPEC成员之间密切合作和与生物技术企业的密切合作,吸引和培养了众多在生化工程领域有建树的年轻人才。本文还对王义翘先生和BPEC对我国生化工程发展的启示和借鉴做了简要的评述。

关键词： MOOC   生物化学   教学改革  

摘要： 作为高等教育与信息化的高度融合体,基于MOOC的混合式教学已成为高校教学改革的新方向。因此,构建具有本校特色的精品在线课程,并探索以此为基础的混合式教学改革的应用效果,具有重要的教学意义。在新乡医学院,生物化学课程为本科临床和护理学专业学生必选的考试课,是基础医学的核心课程之一,并于2019年开始初步实行混合式教学。该文旨在分析MOOC平台现有课程、三全学院特色资源建设及其应用效果,为继续开展混合式教学改革提供支撑与保障。

关键词： 食品安全教育   食品安全标准   生物性污染   跨学科领域   食品卫生   有毒物质   化学物质   食品安全性  

摘要： 食品安全作为一门跨学科领域,主要分析探讨食品加工、存储以及销售等环节,旨在通过食品安全措施排除或降低食品对消费者生命健康造成不良影响的风险。食品安全措施具体包括保障食品卫生以及安全,防范与规避食物中毒以及疾病隐患等,对此,在高校思政教育中融入食品安全教育是新媒体时代背景下的重要课题。由王际辉和叶淑红共同编著、中国轻工业出版社出版的《食品安全学》(第二版)一书,基于国内外相关领域的先进技术和研究成果,以食品安全概述以及相关科学问题为主要研究内容,以科研、教学和生产实际为切入点,具体阐述了生物性污染、环境污染、食品中的有毒物质、化学物质、包装材料和膳食中的不安全因素等对食品安全性的影响,同时引用最新的标准与法规,研究并介绍了食品安全性评价及相关实验、食品安全标准与质量控制等内容。

关键词： Halo-alkaliphilic actinomycetes   Alkaline protease   Repression of protease synthesis   Protease applications   PROTON MOTIVE FORCE   BACILLUS   STABILITY   ENZYMES   PURIFICATION   STABILIZATION   PROTEINASE   IONS  

摘要： A marine haloalkaliphilic actinomycete identified as Nocardiopsis dassonvillei subsp. albirubida (strain OK-14) was screened for its ability to produce extracellular alkaline protease under various physical conditions pertinent to different applications. The strain utilized amino acids as the sole source of nitrogen, displaying repression and derepression phenomenon above the threshold levels. The activity of the partially purified alkaline protease was 1421.7 U/ml/min. The enzyme was optimally active at pH 10 and 60 degrees C. The activity was assessed under various concentrations of NaCl, organic solvents and metal ions. The partially purified alkaline protease was then examined for its suitability in blood de-staining, gelatine degradation and keratinase activity, implicating its relevance in detergent industries, gelatine extraction from X-ray films and degradation of bio-wastes.

关键词： PHYTOCHELATIN SYNTHESIS   AGRICULTURAL SOILS   CADMIUM TOLERANCE   HYPERACCUMULATOR   CAERULESCENS   LEAVES   CULTIVARS   SUNFLOWER   MEMBRANE   TOXICITY  

摘要： The field pennycress (Thlaspi arvense L.) is a sensitive non-accumulator of metals. The main objective of the present work was to evaluate the effects of Cd stress in T. arvense using a physiological approach. Four-week-old plants were exposed to increasing concentrations of Cd (0, 10, 50 and 100 mu M Cd(NO3)(2)) for 14 days. Plants were harvested at days 0, 3, 7 and 14 to assess the following parameters: shoot and root length and fresh weight; osmolality and conductivity in leaves; chlorophyll a and b contents and photosynthetic efficiency in leaves (young and expanded); water content, Cd accumulation and nutrient imbalances in leaves (young and expanded) and roots. Thlaspi arvense presented a reduction of 27% in the length of roots exposed to 100 mu M Cd, and in plants exposed to 50 and 100 mu M Cd, a reduction in the fresh weight of both shoots (53 and 58%, respectively) and roots (58 and 63%, respectively) was observed. In general, in plants exposed to the highest concentrations of Cd, a decrease in leaves osmolality and membrane permeability and in water content of both roots and leaves were observed, as well as several nutrient imbalances. As for the photosynthetic parameters, young and expanded leaves responded differently to Cd stress. Exposed young leaves presented no alterations in photosynthetic efficiency or chlorophyll contents, while expanded leaves of 100 mu M Cd-treated plants showed a reduction of up to 67% in chlorophyll contents and a concomitant reduction of 30% in photosynthetic efficiency. Overall, Cd-induced senescence in the non-accumulator plant T. arvense exposed to high concentrations of Cd, which was measured as a decrease in several physiological and biochemical parameters and nutrient imbalances. These Cd-induced alterations resulted in lower plant growth, which might have further implications on plant performance at the population level.