课程文献中心 更多>>

关键词： 营养与食品卫生学   实践教学   有效策略  

摘要： 营养与食品卫生是中职医学专业必修的内容。随着我国逐年加深对素质教学的重视,过去的营养与食品卫生学和现今社会的要求已经不相符,所以,要利用科学的方法进行教学改革,进一步提高学生的专业水平。本文主要探讨了中职营养与食品卫生学中的问题,并提出一些可行性建议,为教学改革提供更多的参考依据。

关键词： 欧亚经济联盟   食品添加剂   香精香料   加工助剂   合规性   清单   评估技术   欧亚经济委员会  

摘要： 欧亚经济委员会新闻中心8月25日消息:欧亚经济委员会理事会批准对《食品添加剂、香精香料和加工助剂安全》技术法规所采用的标准清单,该清单包含应用及评估技术法规适用范围内产品合规性所必须的规则和研究方法。

关键词： a食品营养  

ISBN: (纸本)9787303261840

关键词： Sodium lactate   Spectroscopic studies   Molecular docking   Bovine serum albumin   BOVINE SERUM-ALBUMIN   BETA-CYCLODEXTRIN INFLUENCES   ASCORBYL PALMITATE   TBHQ  

摘要： Sodium lactate (SL) is a lactic acid salt that is used in the food and pharmaceutical industries due to its antioxidant and antibacterial properties. Therefore, for the first time we investigated the interaction of SL with the bovine serum albumin (BSA) using spectroscopic and molecular modeling studies under physiological conditions. Fluorescence studies were performed at three different temperatures and the attained results showed emission intensity decrease upon addition of SL. Calculated thermodynamic parameters demonstrated that van der Waals interactions and hydrogen bonds were the main forces in the binding of SL to BSA. The negative sign of standard Gibbs free energy (Delta G degrees) showed that the BSA-SL complex formation was a spontaneous molecular interaction process. The results of UV-Vis spectroscopy showed a ground-state complex formation between BSA and SL and confirmed the results of fluorescence quenching study which showed the quenching mechanism was static. Results of molecular docking indicated a stable binding for lactate to BSA on Sudlow II and lowest calculated binding energy for the interaction was -7.87 kcal/mol. Also, the significant role of two amino acid residues (Lys 499, Lys 533) in the binding process of BSA with SL was approved. This investigation provides important insight into the mechanism of sodium lactate interaction with BSA in vitro. (C) 2020 Elsevier B.V. All rights reserved.