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关键词： 虚拟化   云计算   分布式系统   监控系统   数据中心  

摘要： 为了减少各个子单位重复建设数据中心所带来的运营成本,以及避免在新冠疫情下员工的健康风险,中石油已在全球多个国家和地区建设了地区数据中心,提供云端基础服务,而虚拟化技术则是云端基础服务的核心技术。但是,由于各个国家和地区的不同现状,这些数据中心所采用的虚拟化技术不尽相同,这就使得系统监控变得极其困难,甚至有可能需要人工来发送错误通知,这造成了极大人力物力的浪费。论文提出了一种分布式可运行在非同构虚拟化数据中心的监控方案,并进行了小规模验证,证明了这里提出的方案是一种可靠稳定且经济实用的方案。

关键词： 机械设备   管理   维护保养  

摘要： 随着社会经济的不断发展,我国引进了大量先进的机械设备,相关设备的引进在很大程度上提升了生产作业的效率,对于进一步促进我国工业事业的现代化发展,以及城市的发展建设具有重要的意义。现代机械设备往往具有很强的功能性以及复杂性,设备的维护保养水平在很大程度上决定了设备的运行状态,因此想要充分发挥相关机械设备在社会生产中的作用,就需要将相关设备的维护保养重视起来,本文主要从实践的角度出发,对于机械设备的管理,以及维护保养技术进行研究,希望能够保证设备在实际运行中的运行状态。

关键词： Drowsiness detection   Deep learning   ResNet   LSTM   HEAD POSE   EYE STATE   SYSTEM  

摘要： Driver drowsiness is one of the main reasons for deadly accidents, especially on suburban roads. Researchers have used many methods for analyzing videos and detecting drowsiness, and the most up-to-date methods among them are using deep learning. This paper proposes a hierarchical framework comprising deep networks with split spatial and temporal phases referred to as hierarchical deep drowsiness detection (HDDD) network. The proposed method uses ResNet to detect the driver's face, lighting condition, and whether the driver is wearing glasses or not. This phase also causes a significant increase in eyes and mouth detection percentage in the next stage. Afterward, the LSTM network is used to take advantage of temporal information between the frames. The average accuracy of the drowsiness detection system is reached 87.19 percent.

关键词： Scarabaeinae   Tropical forest   Community composition   Defaunation   Functional traits   Secondary seed dispersal   ROBUST VARIANCE-ESTIMATION   FILE-DRAWER PROBLEM   SECONDARY DISPERSAL   SEED DISPERSAL   RAIN-FOREST   ECOSYSTEM FUNCTION   RESPONSE RATIOS   SCARABAEINAE   LAND   MAMMALS  

摘要： Human population growth and the activities resulting in habitat destruction are a threat to biodiversity worldwide. Despite the recognized importance of dung beetles in supporting tropical forest ecosystems, our understanding of their susceptibility to anthropogenic pressures remains limited. Previous research detailed the overall consequences of habitat loss driven by human activities to tropical dung beetle assemblages and traits. The work pointed out main knowledge gaps and outlined future work inspiring a surge in research. After a decade, we build upon the previous review, and bring an update to this topic with the aim of disentangling the confounding drivers impacting dung beetle responses. Using a comprehensive meta-analytical approach, we address the main geographical constraints and limitations, summarize the most up-to-date information, and draw new conclusions on the consequences of human activities to dung beetles. Our results help to draw together the patterns defining how human activities alter dung beetle abundance, species richness, community diversity and evenness. We show that beetle assemblage composition depends upon the origin and intensity of forest conversion, and has consequences for dung beetle associated ecosystem functions. Finally, we demonstrate that the depletion of large vertebrates throughout the tropics has indirect effects on beetle communities. As a consequence, anthropogenic actions are likely to harm dung beetle populations both directly, through habitat loss, and indirectly, through the cascading effects of the loss of large mammals.

关键词： Interoperability   QM/MM   Quantum chemistry   Molecular mechanics  

摘要： The MolSSI Driver Interface (MDI) Project provides a standardized API for fast, on-the-fly communication between computational molecular sciences codes. This greatly simplifies the process of implementing methods that require the cooperation of multiple software packages and enables developers to write a single implementation that works across many different codes. The API is sufficiently general to support a wide variety of techniques, including QM/MM, ab initio MD, machine learning, advanced sampling, and path integral MD, while also being straightforwardly extensible. Communication between codes is handled by the MDI Library, which enables tight coupling between executables using either the MPI or TCP/IP methods. Program summary Program title: The MDI Library CPC Library link to program files: https://***/10.17632/8zppf699hm.1 Developer's repository link:https://***/MolSSI-MDI/MDI_Library Licensing provisions: BSD 3-clause Programming language: C, Python, and Fortran95 Nature of problem: Enabling direct communication of commands and data between independently compiled computational molecular sciences codes with minimal latency and in a manner consistent with the requirements of the MDI Project. Solution method: Inter-code communication via the MPI and TCP/IP communication protocols is implemented within the context of a library, with all choices regarding the communication protocol being made by the end-user at runtime. Messages are validated based on expected data type and length, and self-consistent unit conversions are provided. The library builds via CMake, with support for the Unix, Linux, MacOS, and Windows operating systems and for codes using the C, C++, Python, and Fortran languages. Additional comments including restrictions and unusual features: The MDI Library does not itself perform any scientific calculations, but instead facilitates communication between other codes. The MDI Library is a component of the larger MDI Project, which is desc

关键词： electrophysiology   device interrogation   anesthesia-based electrophysiology   perioperative device management   PACEMAKERS  

关键词： Lung adenocarcinoma   Next-generation sequencing   Drug target   Gene fusion   Atypical variants   CELL LUNG-CANCER   TYROSINE KINASE INHIBITORS   MOLECULAR TESTING GUIDELINE   HER2 MUTATIONS   GENE FUSIONS   PHASE-II   BRAF   ADENOCARCINOMA   AFATINIB   COMBINATION  

摘要： Objectives: Implementation of tyrosine kinase inhibitors (TKI) and other targeted therapies was a main advance in thoracic oncology with survival gains ranging from several months to years for non-small-cell lung cancer (NSCLC) patients. High-throughput comprehensive molecular profiling is of key importance to identify patients that can potentially benefit from these novel treatments. Material and Methods: Next-generation sequencing (NGS) was performed on 4500 consecutive formalin-fixed, paraffin-embedded specimens of advanced NSCLC (n = 4172 patients) after automated extraction of DNA and RNA for parallel detection of mutations and gene fusions, respectively. Results and Conclusion: Besides the 24.9 % (n = 1040) of cases eligible for approved targeted therapies based on the presence of canonical alterations in EGFR exons 18-21, BRAF, ROS1, ALK, NTRK, and RET, an additional n = 1260 patients (30.2 %) displayed rare or non-canonical mutations in EGFR (n = 748), BRAF (n =135), ERBB2 (n = 30), KIT (n = 32), PIK3CA (n = 221), and CTNNB1 (n = 94), for which targeted therapies could also be potentially effective. A systematic literature search in conjunction with in silico evaluation identified n = 232 (5.5 %) patients, for which a trial of targeted treatment would be warranted according to available evidence (NCT level 1, i.e. published data showing efficacy in the same tumor entity). In conclusion, a sizeable fraction of NSCLC patients harbors rare or non-canonical alterations that may be associated with clinical benefit from currently available targeted drugs. Systematic identification and individualized management of these cases can expand applicability of precision oncology in NSCLC and extend clinical gain from established molecular targets. These results can also inform clinical trials.

关键词： Distracted driving   Naturalistic driving   Speed   Behavioral adaptation   Risk compensation   Observational study  

摘要： Considering the number of people who have been involved in crashes associated with driver distractions, it is important to understand the characteristics of distracted driving on public roadways. While experiments have indicated that driver distractions are associated with slower driving speeds, the methodologies tend to have limited external validity. Observational studies are often conducted under limited circumstances ? be it time or location. Therefore, in order to better understand the nature of driver distractions, the authors investigated the relationships between driving speed, posted speed limits, and phone handling frequency through naturalistic driving data obtained (via disruptive technology) from 8,240 mobile application users on state-maintained highways throughout Texas. As a measure of manual distractions, a phone handling rate (PHR; times/hours driven) was calculated based on phone rotations. Within-subject comparisons were drawn for driving speed and posted speed limits under normal driving conditions and distracted conditions. The analysis revealed a strong negative correlation between PHR and driving speed (rs =-0.87). Paired t-tests revealed significantly lower driving speeds (p = 0.000 < 0.01, d =-0.48, eta = 0.69) and posted speed limits (p = 0.000 < 0.01, d =-0.20, eta = 0.42) during phone handling events when compared to driving without phone handling. On average, users drove 3.26 mph slower in distracted conditions than in undistracted conditions. Driving speed had a larger effect size than posted speed limits. The findings were in line with existing theories and experiments as well as other observational studies conducted at fixed locations. Although this research did not reveal causal relations, it is noteworthy that speed reduction with manual distractions was observed under real road conditions. Spatial analyses are recommended to conduct in order to paint a more thorough picture of speed reduction, its relationship to space, and crash

关键词： Theory of planned behaviour   High school road safety education program   Intentions and willingness to ?speak up?   Speeding   Mobile phone use while driving   Passengers   IMPLEMENTATION INTENTIONS   PASSENGERS   WILLINGNESS   HEALTH   METAANALYSIS   PREDICTORS   PRESSURE  

摘要： Risky driving behaviours such as mobile phone use and speeding remain common among young people, thereby contributing to their over-representation in road crashes. There is much evidence that similar-aged peer passengers can have a negative impact on a young driver's behaviour; however, there is also research that supports the positive influence that peer passengers can have when they speak up about risky behaviours. Road safety education programs, such as the Royal Automobile Club of Queensland's (RACQ) Docudrama program, aim to help young people understand the important role they play as peer passengers and, thus, the importance of being willing to speak up to a driver who may be engaging in risky behaviours. Extending on a previous evaluation of the RACQ Docudrama program, the current study uses an Extended Theory of Planned Behaviour framework to evaluate the program's effectiveness in influencing peer passengers' intentions and self-reported behaviour in speaking up against risky driving behaviours, including mobile phone use and speeding. A repeated-measures design compared participants' responses over 3 time-points: Time 1 (one month before participating in the program), Time 2 (immediately after having participated in the program), and Time 3 (three months after program participation). The results indicate that levels of anticipated regret for having not spoken up were higher following participation in the program suggesting that it encouraged young people to consider how they would feel if something was to happen and they, as passengers, had not tried to prevent it by speaking up. Three months after participating in the program, the majority of participants reported that they were positively influenced by the program in terms of engaging in safer behaviours as passengers; although the significant effects regarding improvements were observed only immediately after participating in the program. The implications of such findings are discussed in terms of the n

关键词： Driver reading performance   Bilingual traffic sign   Sign layout design   Bilingual typography   VISUAL-SEARCH   LINE LENGTH   SPEED  

摘要： Chinese-English bilingual traffic signs (CEBTS) are widely applied in public spaces within China, but few studies have addressed the spatial arrangement of the two languages on CEBTS and road standards provide little guidance for it. This study investigates whether changes in ?separating space?, the vertical space between bilingual place names on CEBTS, affects driver reading performance. Ten sign combinations were developed using variations in the sign?s graphic complexity, total number of place names, and the spatial distribution of the place names. Each sign was displayed in a 3D graphics rendered clip of someone driving towards the road sign in random order. Participants identified destinations by reading the signs shown in the clip. The speed and the accuracy of responses was recorded. 39 English-reader participants were recruited and equally split into three groups. Three levels of separating space 0.5H, 0.75H and 1H; H refers to one Chinese character height, were prepared according to a between-subject factorial design. The results show that the separating space affected the response time regardless of sign combinations. Both 0.5H and 0.75H separations caused significant faster reading time and higher accuracy than 1H, but 0.75H appears to achieve better result. The findings contribute to the legibility research concerning bilingual signs with two very different character sets. This study considers improving sign legibility through spatial arrangement of the bilingual text, which is currently limited in the field of Chinese road sign legibility. The findings could inform future standards for Chinese-English road signs.