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关键词： 土地利用   整治   生态系统服务   生态功能分区   FCM聚类  

摘要： 生态系统服务功能分区是科学管理生态系统的重要手段。国土空间整治能够通过综合治理闲置、低效和生态退化国土资源,改变国土空间结构与布局,从而对生态系统功能产生影响。现有研究较少关注土地整治措施对未来生态系统服务空间集聚模式的潜在影响作用,整治措施的生态导向性有待提升。因此,该研究以山东招远市为例,设计了基准情景、废弃矿区修复情景以及城乡建设用地整治情景,定量化预测生态系统服务变化特征,并运用模糊C均值聚类算法开展生态系统功能区划定。结果表明,整治情景下土地利用数量结构变化显著,各生态系统服务能力均有所提升。全域可以划分为生态综合区、生境保育区、固碳释氧区、固碳产粮区、生态维护区5个生态功能区。与基准情景相比,废弃矿区修复情景下各生态功能区60%生态系统服务水平持平,28%处于劣势,仅12%显著提升。城乡建设用地整治则能够显著提升全域自然娱乐能力,总体增长了1.89%。生境保育区的自然娱乐和粮食生产能力平均值分别增加了0.01和0.10,固碳释氧区的生境质量、水源涵养能力分别增长了20.69%和100%。研究表明全面提升生态系统多功能性需要综合开展多元的国土空间整治措施。

摘要： Purpose/Objective(s) High stage cutaneous squamous cell carcinoma (CSCC) has an elevated risk of recurrence (5-25%). Current staging systems stratify patients rely on tumor factors only. We sought to develop an RPA incorporating patient-, tumor-, disease-, and treatment-related factors to identify prognostic subgroups for high-stage CSCC patients receiving definitive therapy. Materials/Methods All high-stage CSCCs, defined as Brigham & Women's Hospital (BWH) tumor (T) staging system T2B and T3, treated with curative intent were included. Recurrence-free survival (RFS) and overall survival (OS) were estimated using the Kaplan-Meier method and compared by log rank test. Recursive partitioning analysis (RPA) was performed to identify prognostic factors for RFS and OS. Results A total of 444 patients (76% male, 95% Caucasian, median age 74 years) with 523 primary tumors were included. Median follow up was 31 months (range 1-194). 31% of patients were immunosuppressed (organ transplant 13%, chronic lymphocytic leukemia (CLL) 14%, and other reasons 3%). 432 tumors were BWH T2b and 91 were BWH T3, of whom 12% were node-positive, 32% node-negative, and 56% unknown nodal status. 33% of patients experienced recurrence. Immunosuppression , recurrent tumor , perineural invasion (PNI), and lymphovascular space invasion (LVSI) were associated with significantly worse RFS (median RFS 23 months, 95% CI, 19-28), while immunosuppression, lymph node positivity, and extranodal extension (ENE) were associated with significantly worse OS (median OS 40 months, 95% CI, 33-46). RPA identified 4 prognostic subgroups with distinct RFS patterns ( P < 0.0001): class I included age < 77 years without LVSI (N = 212, 2-year RFS: 63%; 95% CI, 56-70%), class II included age ≥ 77 years without PNI (N = 132, 2-year RFS: 44%, 95% CI, 36-55%), class III included age < 77 years with LVSI (N = 36, 2-year RFS: 29%; 95% CI, 17-50%), and class IV included age ≥ 77 years with PNI (N = 60, 2-year RFS: 25%; 95%

摘要： Purpose/Objective(s) To investigate the timing and pattern of recurrence in stage IIIA-N2 non-small cell lung cancer (NSCLC) patients after complete resection and adjuvant chemotherapy . Materials/Methods The study cohort included pathologically confirmed stage IIIA-N2 NSCLC patients treated with complete resection and adjuvant chemotherapy from 2003 to 2015 in our single institution. Recurrence was categorized as local-regional recurrence (LRR), distant metastasis (DM) and both LRR and DM. The risk distribution was assessed by using clinical and pathological factors. The hazard rate function and competing risk analysis were used to evaluate the recurrence dynamics. The Gray's test was employed to estimate the cumulative recurrence rates and compare the differences between groups. Results Among 854 patients, 61.9% had multiple station N2 involvement. The 1, 3 and 5-year cumulative incidence rates of recurrence was 16.85%, 50.74% and 67.37%, respectively. Of the 510 patients who experienced recurrence, 95 (18.6%) experienced LRR, 285 (55.9%) experienced DM, whereas 130 (25.5%) had both LRR and DM. The hazard rate function for overall recurrence revealed a continuous increase between 0-18 months after surgery, consistent high level during 8-48 months and marked decline thereafter. And the DM displayed a hazard rate curve similar to that of overall recurrence. However, a double-peaked pattern of hazard rate was present in LRR and both LRR and DM. What's more, the peak recurrence frequency of DM differed by organs. A comparison of clinical and pathological factors revealed that patients with lower pT stage, single pN2 station and postoperative radiotherapy had a lower recurrence risk but similar pattern of recurrence. Conclusion The recurrence risk of IIIA-N2 NSCLC after complete resection and adjuvant chemotherapy increased to a high level in 18 months and maintained continuously high till 48 months after surgery, which hinted necessity of intensive follow-up during th

关键词： 公路桥梁   伸缩缝破坏   处理措施  

摘要： 为更好地完成工程建设任务,需要对伸缩缝破坏问题进行深入研究,解决及规避基础层面的诱因外,确保桥面施工的稳定,并执行更好地施工方法来增加路面施工的可靠性。然而,在一些地方,往往会出现梁端位置设置不合理的问题,这是由于工程建设的体量大、任务繁杂所导致,只有基于此类弊端现象,以及梁端、桥梁交接位置设置不合理的问题,避免此类弊端现象的存在,才能确保桥面车辆的行驶稳定,发挥出一定的保护作用,以规避频发性较高的问题。

关键词： ALC   装配式   内隔墙板  

摘要： 蒸压加气轻质混凝土隔墙板(简称ALC板)自重轻,延性好。相对传统砌体隔墙,安装方便,所产生的建筑垃圾少。通过ALC板与传统隔墙板综合性能对比,分析了ALC板工作性能,同时结合实际施工案例,介绍了ALC板施工工艺,为ALC板施工提供借鉴。

关键词： 城市阳台   城市滨水区   生态设计   雨洪调蓄   生态净水   亲水   立体游憩  

摘要： 滨水区城市阳台同时具备生态重要性、高游憩需求、城市形象展示等多种功能诉求。在生态文明背景下,秉承长江“生态优先、绿色发展”的理念,南京市江北新区核心区城市阳台的设计提出了兼顾雨洪调蓄、净化等生态系统服务功能与构建多层次游憩网络的设计方法,可为滨水区城市阳台设计提供参考。

关键词： 建筑结构   裂缝   伸缩缝  

摘要： 建筑结构裂缝的产生大大威胁到了建筑的安全性和稳定性。基于此,文章探究了建筑结构中裂缝的主要类型,分析了建筑结构裂缝的危害性及其成因,提出了建筑结构裂缝的规避措施。

关键词： 装配式建筑   立面设计   技术要点  

摘要： 随着地区经济的不断发展,区域内的建筑规模也在不断扩大。这种迅速膨胀的建筑规模不仅直接影响了传统的建筑模式,还间接影响了经济发展速度。所以为了适应快速增长的建筑需求,部分地区开始抛弃传统的建筑形式,并尝试大范围普及装配式建筑技术,以便提高现代建筑的建筑效率以及建筑质量。不过由于装配式建筑出现时间较短,所以大部分施工团队并没有掌握其核心技术,尤其是在立面设计当中。经验的缺乏也导致大部分的建筑都难以满足建筑方的需求。因此,为了提高装配式建筑的立面设计质量,文章分析了装配式建筑的主要特征,并总结了相关的技术要点,希望能够丰富当今装配式结构的建筑体系。