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关键词： Combinational therapy   Artemisinin   Resistance   Efficacy   Publication bias   Prisms   Meta-analysis   Systematic review  

关键词： 计算机网络   实验教学   Cisco   Packet   Tracer  

摘要： 笔者以当前高校计算机网络课程实验教学面临的典型问题为背景,分析了在计算机网络实验课程中引入Cisco Packet Tracer工具的必要性和重要意义,并总结了在运用Cisco Packet Tracer工具进行实践教学中遇到的一些普遍问题及解决方法,最后总结了将Cisco Packet Tracer工具引入计算机网络课程实验教学的显著成效。

关键词： Rectal cancer   Recurrence   Re-irradiation   Surgery   Complication   TOTAL MESORECTAL EXCISION   STEREOTACTIC BODY RADIOTHERAPY   LOCALLY RECURRENT   PREOPERATIVE RADIOTHERAPY   MULTIMODALITY TREATMENT   SURGICAL RESECTION   COLORECTAL-CANCER   PELVIC RECURRENCE   POOLED ANALYSIS   HYPERTHERMIA  

摘要： Background and purpose: Re-irradiation might yield local control (LC) or palliation for locoregionally recurrent rectal cancer (LRRC), but iatrogenic complications are a possible hindrance. We aimed to evaluate the efficacy of re-irradiation to determine optimal treatment of LRRC. Methods: We performed a systematic review of PubMed, MEDLINE, Cochrane Library, and Embase. Results: A total of 17 studies involving 744 patients with LRRC were included; median OS ranging from 10 to 45 months (median: 24.5 months). Pooled 1-, 2-, and 3-year OS rates for all patients were 76.1%, 49.1%, and 38.3%, respectively. For patients who underwent re-irradiation and surgery (OP group), these pooled rates were 85.9%, 71.8%, and 51.7%, respectively. For patients who underwent re-irradiation but not surgery (non-OP group), pooled 1-, 2-, and 3-year OS rates were 63.5%, 34.2%, and 23.8%, respectively. The OS difference between both groups was significant for all 3 years (P < 0.05). Pooled 1-, 2-, and 3-year LC rates for the OP group were 84.4%, 63.8%, and 46.9%, and for the non-OP group were 72.0%, 54.8%, and 44.6%, respectively, without significant differences. Pooled grade > 3 acute and late complication rates were 11.7% and 25.5% in the OP and non-OP groups, respectively. Patients who underwent surgery had a higher risk of grade > 3 late complications (odds ratio: 6.39). Pooled symptomatic palliation rate was 75.2%. Conclusions: Re-irradiation with or without surgery for LRRC showed oncologic and palliative efficacy. Salvage treatment including re-irradiation and surgery showed higher survival, but the late complication was significantly increased with concomitant surgery. (C) 2019 Elsevier B.V. All rights reserved.

关键词： 地理信息系统   测绘   数据  

摘要： 在现代化社会的快速发展中,工程项目建设规模在不断扩大,社会各界对工程项目的功能提出了更加严格的要求,尤其是测绘工程,现已呈现出模块化、自动化和数字化的发展趋势。地理信息系统是测绘工程中的关键技术之一,其具有综合评价分析、空间查询和空间分析等功能,为测绘结果的准确性提供了保障,在很大程度上提高了测绘工程的质量和效率。基于此,论文阐述了地理信息系统的相关内容,研究了地理信息系统在测绘中的应用。

关键词： 新工科   建筑学教育   人才培养   建筑设计  

摘要： 在新技术、新业态、新模式影响下我们的建筑市场发生着日新月异变化,社会对建筑设计师的能力要求愈加全面。随着教育部新工科人才培养模式的提出明确我们培养的学生应当成为基础扎实、动手能力强、具有创新意识与工匠精神的复合型人才,这些素质的培养需要我们每一位建筑学教育工作者深入思考并积极行动。

关键词： 新课程改革   初中历史教学   教学经验  

摘要： 在教学改革的新目标下,为提高学生自发性学习的能力,让学生成为学习的主人,教师应当作为辅助角色,通过各种教学措施激发学生的兴趣。社会不断发展,文明不断优化,教学方式的改革也进入了一个全新时代。教学改革虽然改良了传统教学模式,但由于传统教学已经延续了太长时间,导致人们仍旧只看重考试成绩。本文根据笔者的教学经验总结了提高历史教学质量的重要性。